Accordingly, for such patients, doses below those usually recommended should be administered cautiously. Alcoholic beverages should not be consumed during metronidazole therapy super pigiai flagyl and for at least three days afterward because abdominal cramps, nausea, vomiting, headaches, and flushing may occur. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Patients with severe hepatic disease metabolize metronidazole slowly, with resultant accumulation of metronidazole and its metabolites in the plasma.